PDO Hepatoxicity Assessment In-Vivo Studies: ODX & PDX IF Imaging Drug Testing

Staining assays of major cancer signaling pathways can be offered. Assessment for active/total b-catenin, pAkt (Thr308) / total Akt, pERK (Thr202, Tyr201) / total ERK1 / 2, p-SRC (Tyr 527 inactivating) / pSRC (Tyr 416 activating) / total SRC, cytoskeletal actin / tubulin staining, and multiplex IF staining are currently available.   

Immunofluorescence staining of Src and Phospho-Src  

DAPI

Antibo​dy

Merged