Our Organoid Lab is actively engaged in developing PDOs
from a broad spectrum of human cancers. Established
pipeline analytics support drug selection based on genetically-annotated PDOs
and small-molecules chemical screens. Our lab brings together cancer
scientists, specialist technical staff and partnership with clinicians to
advance PDO applications in new and existing drug discoveries. We welcome
R&D collaborations and commercial partnerships.
Areas of focus:
Personalized Medicine: Select
suitable drug options for individual patient through genome-guided PDO drug
testing to assist clinical decision. A report on drug sensitivity profile will
be provided to users of this service.
Drug Discovery: Provide
a PDO platform for preclinical drugs testing and pipeline compounds screening.
PDO models from normal liver are also available to assess new drugs / compounds
for hepatoxicity. A full report on every compound screened will be
provided.
Living Biobank of healthy and tumor PDOs that represent a
unique repertoire from East Asian ethnicity. PDO
lines established from liver cancer, colon cancer, rectal cancer, lung
adenocarcinoma, pancreatic ductal adenocarcinoma and triple negative breast
cancer are accessible for academic research and commercial licensing. The
Office of Research and Knowledge Transfer Services (ORKTS) under The Chinese
University of Hong Kong (CUHK) will be liaised for MTA,
contractual research and commercial interests.
For services request, research collaboration and
commercial purposes, please contact us at
phoebeman@surgery.cuhk.edu.hk.
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